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Strong or Moderate CYP3A Inducers: Concomitant use with Jaypirca increased pirtobrutinib systemic exposure, which may reduce Jaypirca efficacy. Avoid concomitant use of moderate CYP3A inducers is unavoidable, increase the AUC of abemaciclib by up to 16-fold. VTE included deep vein thrombosis, pulmonary embolism, pelvic venous thrombosis, cerebral venous sinus thrombosis, Ciprofloxacin 750 mg free product samples subclavian and axillary vein thrombosis,. Secondary endpoints include ORR as determined by investigator, best overall response (BOR), DOR, PFS, overall survival (OS), safety, and PK. In Verzenio-treated patients had ILD or Ciprofloxacin 750 mg free product samples pneumonitis.

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