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Optimize management of cardiovascular risk factors, such as hypertension, diabetes, or dyslipidemia. TALZENNA is indicated in combination with enzalutamide for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC), and non-metastatic castration-resistant prostate. TALZENNA is first and only PARP inhibitor approved for use with an existing standard of care (XTANDI) for adult patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. Select patients for therapy based where to buy Amlodipine 10 mg in Toronto on an FDA-approved companion diagnostic for TALZENNA.
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A diagnosis of PRES requires confirmation by brain imaging, preferably MRI. The primary endpoint of the trial was rPFS, and overall survival (OS) was a key secondary endpoint.
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