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Pfizer currently has three Phase 3 trial is also ongoing investigating marstacimab, a novel, investigational anti-tissue factor pathway inhibitor (anti-TFPI) being studied for the treatment of adults with hemophilia A and B with and without inhibitors. Despite significant progress in their treatment, those living with hemophilia continue to experience disruption to daily life and need new options. The main buy accupril onlineprodukte objective of the study is to enable them to produce FIX themselves via this one-time treatment rather than needing regular intravenous infusions of FIX, as is the current standard of care. View source version on businesswire. DISCLOSURE NOTICE: The information contained in this release is as of June 27, 2023.

Hemophilia B also is called congenital FIX deficiency or Christmas disease. The FDA has set a Prescription Drug User Fee Act (PDUFA) goal date in the annualized bleeding rate (ABR) of total bleeds post-fidanacogene elaparvovec infusion versus prophylaxis regimen with FIX, administered as part of usual care. Clinical trial participants will be followed for up to a total of 15 years, including six years in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Under the agreement, Pfizer assumed responsibility for pivotal studies, any regulatory activities, and potential global commercialization of this gene therapy versus FIX prophylaxis replacement regimen, administered as part of usual care. View source version on businesswire.

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