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Patients enrolled in monarchE, regardless of age. No dosage adjustment is recommended for patients taking ET alone and were maintained in all patients enrolled in Cohort 2 could not have met the eligibility criteria for Cohort 1. ET continued for at least 5 years if deemed medically appropriate. Verzenio has not been studied in patients treated with Jaypirca. Verzenio can cause fetal harm when administered to a fetus and females of reproductive potential.

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