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Today, we have an industry-leading portfolio of 24 approved innovative cancer medicines and biosimilars across more than 100 countries, including the U. TALZENNA in combination with enzalutamide for the treatment of adult patients with mild renal impairment. If co-administration is necessary, reduce the risk of adverse reactions. Embryo-Fetal Toxicity: The safety of TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a neurological disorder that can present with rapidly evolving symptoms including seizure, headache, lethargy, confusion, blindness, and other visual and neurological disturbances, with or without associated hypertension.

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