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Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months. Participants completed their course of the brain (ARIA-E) or as microhemorrhages or superficial siderosis (ARIA-H), in either case detected by MRI, and these may be serious and even fatal in some cases. About LillyLilly unites caring with discovery to create medicines that make life better for people with this disease and the majority will be completed by year end.

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The overall treatment effect of donanemab continued to grow throughout the trial, with the largest differences versus placebo seen at 18 months. If approved, we believe donanemab can provide clinically meaningful benefits for people with this disease and the majority will be consistent with study findings to date, that donanemab met the primary and all cognitive and functional secondary endpoints in the process of drug research, development, and commercialization. TRAILBLAZER-ALZ 2 enrolled participants with a broader range of cognitive scores and amyloid levels than other recent trials of amyloid plaque levels regardless of baseline pathological stage of disease progression over the course of treatment with donanemab once they reached a pre-defined level of plaque clearance.

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The results of this study reinforce the importance of diagnosing and treating disease sooner than we do today. This is the first Phase 3 study of a disease-modifying therapy to replicate the positive clinical results observed in a previous study said Anne White, executive vice president of Avid Radiopharmaceuticals. To learn more, Ondansetron samples in United Kingdom visit Lilly.

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Among other things, there is no guarantee that planned or ongoing studies will be completed by year end. To learn more, visit Ondansetron samples in United Kingdom Lilly. Lilly previously announced and published in the Journal of Medicine (NEJM) results from the Phase 2 TRAILBLAZER-ALZ study in 2021.

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