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None of the SAEs were deemed related to pregnancy. None of the SAEs were deemed related to pregnancy. Polysaccharides conjugated to CRM have been successfully used by Pfizer in its pneumococcal vaccines, which have a proven track record of safety and immunogenicity in 360 healthy pregnant individuals carry GBS bacteria in their body and may pass it along to their baby during or prior to birth. Annually, there are an estimated 394,000 GBS cases worldwide, which cause at least 138,000 stillbirths and infant deaths each year.
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