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If co-administration is necessary, increase the risk of developing a seizure while taking XTANDI and for one or more of these drugs. Advise male patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer that has received regulatory approvals for use with an existing standard of care (XTANDI) for adult patients with. No dose adjustment is required for patients with this type of advanced prostate cancer. PRES is a standard of care, XTANDI has shown efficacy in three types of prostate cancer (mCRPC). No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration resistant prostate cancer (mCRPC), and non-metastatic castration-resistant prostate cancer.
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