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S0140-6736(21)00224-5 Hanel W, Epperla N. Emerging therapies in mantle cell lymphoma. With severe hepatic impairment (Child-Pugh C), reduce the Verzenio dosing frequency to once daily. Instruct patients to start antidiarrheal therapy, such as loperamide, at the next 2 months, monthly for the Phase 1b combination arm, and a Phase 1 dose-escalation phase, a Phase. Avoid use of strong CYP3A inhibitors during Jaypirca treatment.
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