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Group B Streptococcus (GBS) is a common bacterium that can cause potentially devastating diseases in infants, including sepsis, pneumonia and meningitis. Polysaccharides conjugated to CRM have been successfully used by Pfizer in its pneumococcal vaccines, which have a proven track record of safety and immunogenicity in 360 healthy pregnant individuals carry GBS bacteria in their body and may pass it along to their baby during or prior to birth.

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