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Lilly previously announced and published in the process of drug research, development, and commercialization. This risk should be managed with careful observation, monitoring with MRIs, and appropriate actions if ARIA is detected. Participants in TRAILBLAZER-ALZ 2 were stratified by their level of tau, a predictive biomarker for disease progression, into either a low-medium tau group (sometimes referred to as intermediate tau) or a high tau group, which represented a later pathological stage of disease progression.