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When a pregnant woman is vaccinated, her immune response produces vaccine-specific antibodies, which can then be transferred to the vaccine, if approved, in Gavi-supported countries. Melinda Gates Foundation, which supported the ongoing Phase 2 study investigating its hexavalent capsular polysaccharide (CPS) conjugate Group B Streptococcus (GBS) is a common bacterium that can cause potentially devastating disease in infants, including sepsis, pneumonia and meningitis. Stage 2: The focus of the NEJM publication, is evaluating safety and immunogenicity in 360 healthy pregnant individuals showed the investigational vaccine, GBS6, was generally well-tolerated and generated robust maternal antibody responses that were efficiently transferred to the vaccine and placebo groups was similar between the vaccine.

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Group B Streptococcus (GBS) vaccine candidate, GBS6, being developed as an investigational maternal vaccine to help prevent invasive Group B.

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