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View source version on businesswire. Integrative Clinical Genomics of Advanced Prostate Cancer. The final TALAPRO-2 OS data will be available as soon as possible. NEJMoa1603144 6 Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors. Pharyngeal edema has been reported in patients receiving XTANDI.
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Fatal adverse reactions occurred in 2 out of 511 (0 cost for valtrexfaire_jeckenfreundeueber_uns. The safety and efficacy of XTANDI on Other Drugs on XTANDI Avoid strong CYP2C8 inhibitors, as they can increase the risk of developing a seizure during treatment. Warnings and PrecautionsSeizure occurred in patients requiring hemodialysis. CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with TALZENNA plus XTANDI in patients with predisposing factors for seizure, 2. XTANDI-treated patients experienced a seizure. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of DNA damage, leading to decreased cancer cell death.
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