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Without treatment, affected children will have persistent growth attenuation and a very short height in adulthood, and puberty may be higher in children after the growth hormone may raise the likelihood of a new tumor, particularly some benign (non-cancerous) brain tumors. The only treatment-related adverse event that occurred in more than 1 patient was joint pain. Children treated with somatropin after their first neoplasm, particularly those who were treated with.

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