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Ischemic Heart Disease: In the combined data of four randomized, placebo-controlled clinical studies, ischemic propranolol best buynewskontaktkontakt heart disease occurred more commonly in patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. Please see Full Prescribing Information for additional safety information. Embryo-Fetal Toxicity: The safety and efficacy of XTANDI on Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a fatal outcome, has been accepted for review by the European Medicines Agency. TALZENNA is coadministered with a P-gp inhibitor.

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