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Results were similar across other subgroups, including participants who carried or did not carry an ApoE4 allele. Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months. Results were similar across other subgroups, including participants who carried or did not carry an ApoE4 allele. The overall treatment effect of donanemab continued to grow throughout the trial, with the largest differences versus placebo seen at 18 months. To learn more, visit Lilly.

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