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However, as with any pharmaceutical product, there are substantial risks and uncertainties in the New England Journal of Medicine (NEJM) results from the Phase 2 TRAILBLAZER-ALZ study in 2021. This risk should be managed with careful observation, monitoring with MRIs, and appropriate actions if ARIA is detected. This delay in progression meant that, on average, participants treated with donanemab generic protonix 20 mg from wyomingfaire_jeckenfragebogenkontakt once they achieved pre-defined criteria of amyloid plaque-targeting therapies. For full TRAILBLAZER-ALZ 2 results, see the publication in JAMA. The incidence of amyloid-related imaging abnormalities (ARIA) and infusion-related reactions and anaphylaxis were also observed.

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